
Product Insights
Equate Children's Multi-Symptom Cold is an over-the-counter liquid medicine sold in the United States that combines acetaminophen, diphenhydramine HCl, and phenylephrine HCl to relieve fever, cough, nasal congestion, and sore throat in kids. Each 10 mL dose delivers 325 mg of acetaminophen, 12.5 mg of diphenhydramine and 5 mg of phenylephrine, providing rapid symptom control while the liquid format allows easy dosing for children. However, the formula carries serious safety risks, including potential liver damage from acetaminophen overdose, severe skin reactions, sedation from diphenhydramine, and contraindications with MAOI drugs, so parents must follow dosing limits and avoid concurrent use with other acetaminophen-containing products.
Comparative Analysis
Positioned as a budget-friendly, liquid, multi-symptom cold remedy for children, this Equate product differentiates itself in the US OTC market by bundling three active agents in a single dose, offering fast fever reduction, antihistamine cough relief, and nasal decongestion in a kid-friendly formulation.
Ingredients
(in each 10 mL) Purpose Acetaminophen 325 mg....................... reliever/ fever reducer Diphenhydramine HCI 12.5 mg.............Antihistamine/ cough suppressant Phenylephrine HCI 5 mg................Nasal decongestant Uses temporarily relieves these common cold and flu symptoms: ⚫ cough sore throat nasal congestion ⚫ runny nose ⚫ minor aches and pains headache ⚫ sinus congestion and pressure sneezing ■temporarily reduces fever controls cough to help your child get to sleep Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if your child takes more than 5 doses in 24 hours, which is the maximum daily amount with other drugs containing acetaminophen. Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: if sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea or vomiting, consult a doctor promptly. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. to make a child sleepy with any other product containing diphenhydramine, even one used on the skin in a child who is taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your child's prescription drug contains an MAOI, ask a doctor or pharmacist before giving this product.
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Frequently Asked Questions
Everything you need to know about children's multi symptoms cold.







